Description: Lecture, three hours; laboratory, one hour. Requisites: courses 200A, 200B. Strongly recommended: variety of other graduate coursework. Sample size and power analysis methods for common study designs, including comparison s of means and proportions, ANOVA, time-to-event data, group sequential trials, linear regression, cluster randomized trials and multilevel data, with emphasis on designing randomized trials. Discussion also of multiple endpoints. S/U or letter grading.

Units: 4.0