COM SCI C121
Probabilistic Models in Computational Genomics
Description: (Formerly numbered CM121.) Lecture, four hours; discussion, two hours; outside study, six hours. Requisites: course 32 or Program in Computing 10C with grade of C- or better, and one course from Civil and Environmental Engineering 110, Electrical and Computer Engineering 131A, Mathematics 170A, Mathematics 170E, or Statistics 100A. Prior knowledge of biology is not required. Designed for engineering students as well as students from biological sciences and medical school. Introduction to probabilistic models in the context of genomics, with emphasis on concepts and inventing new computational and statistical techniques to analyze genomic data. Concurrently scheduled with course C221. Letter grading.
Units: 4.0
Units: 4.0
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Most Helpful Review
Fall 2025 - Prof Pimentel does the first 7ish weeks of class: He covers a lot of stats which I wasn't expecting, but it wasn't that bad if you've taken stats classes before. There's a couple coding assignments and one math HW, but nothing is too bad if you pay attention (TA's are also very helpful in OH). Practice midterm prepared us extremely well for the midterm, which was very fair. Prof Eskin takes over for the final weeks of class: His lectures were mostly about new science LLMs and other random topics he found interesting, which was neat to hear about and a nice change of pace. We had one pretty chill assignment and that was it for the last month of class. The midterm could replace the final so I didn't have to take the final which was really nice and appreciated. Overall, this class is a pretty chill CS elective and not that much work, and the professors are pretty cool. Definitely would recommend.
Fall 2025 - Prof Pimentel does the first 7ish weeks of class: He covers a lot of stats which I wasn't expecting, but it wasn't that bad if you've taken stats classes before. There's a couple coding assignments and one math HW, but nothing is too bad if you pay attention (TA's are also very helpful in OH). Practice midterm prepared us extremely well for the midterm, which was very fair. Prof Eskin takes over for the final weeks of class: His lectures were mostly about new science LLMs and other random topics he found interesting, which was neat to hear about and a nice change of pace. We had one pretty chill assignment and that was it for the last month of class. The midterm could replace the final so I didn't have to take the final which was really nice and appreciated. Overall, this class is a pretty chill CS elective and not that much work, and the professors are pretty cool. Definitely would recommend.
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