M PHARM M205A

Introduction to Chemistry of Biology

Description: (Same as Chemistry CM205A.) Lecture, three hours; discussion, one hour. Enforced requisite: Chemistry 153A with grade of C- or better. Introduction to chemical biology. Topics include computational chemical biology, utility of synthesis in biochemical research, peptidomimetics, designed reagents for cellular imaging, natural product biosynthesis, protein engineering and directed evolution, cell biology of metal ions, imaging metal ions in cells, metal-containing drugs. Letter grading.

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