Neurotransmitters in Human Disorders of Motor and Cognitive Function
Description: Lecture, three hours. Designed for graduate students. Detailed analysis of molecules involved in interneuronal communication processes (i.e., neurotransmitters, neurohormones, "neuromodulators," neurotropic agents). Discussion of their roles in normal brain physiology, followed by detailed analyses of their perturbations in various disease states. Particular emphasis on current and past thinking about Alzheimer's disease, Parkinsonism, Huntington's disease, and Down's syndrome dementia. Letter grading.