I took LS3 with Tamanoi 11W and it was meh.
You have to know every detail on every single one of his slides for his tests, but I would still say his tests are fair. It's just a ton of information to commit to memory.

Also, we only had one midterm and final so the midterm was a big deal.

I didn't really like his lectures that much. He would jump around between slides and didn't organize the topics very well. It was often difficult to keep track of when we were discussing eukaryotes or prokaryotes.

I did not learn much from lecture but I would go slide by slide afterward and read the corresponding sections in the book to help understand the lecture slides. This helped A LOT because for me, I need to understand what I'm memorizing. I found the textbook (Molecular Biology by Robert Weaver) to be extremely helpful. It is a very good textbook. Although you can do okay without every using the textbook because the tests are only based on the lecture slides, the textbook is very helpful in elucidating the slides as the slides don't have all the info you need to fully understand the concepts.